Main Article Content

Abstract

Background: COPD (chronic obstructive pulmonary disease) is a chronic disease characterized by persistent airflow limitation and is a major cause of morbidity and mortality. Objectives: This study aimed to analyze potential predictors of length of hospitalization (length of stay/   LOS) of COPD patients in the Anutapura Hospital, Central Sulawesi Province, Indonesia. Material and Methods: This study is an analytical descriptive using a cross-sectional design. The data were collected from medical records of COPD patients at Anutapura Hospital, Central Sulawesi Province, during 2018-2021. Information about demographic data (age, gender, weight), clinical data (comorbidities, single/combination antibiotics, route of antibiotic administration, type of antibiotics, oxygen therapy, history of hospital admission due to pneumonia, with/without exacerbations), and non-clinical data (type of insurance and treatment class) were extracted. Multivariate linear regression was used to identify the predictors of LOS. Results: A total of 210 COPD patients were identified. The results of univariate analysis showed that there were several potential predictors of LOS in COPD patients (p < 0.25), namely: age (B: 0.03, 95% CI: 0.01-0.05), treatment class (B: 1.16, 95% CI: 0.01-2.33), exacerbation (B: 0.55, 95% CI: -0.24-1.35), comorbidities (B: 0.68, 95% CI: 0.25-1.12), and single/combination antibiotics (B: 1.43, 95% CI: 0.33- 2.54). The results of the multivariate analysis indicated that the older (B: 0.03, 95% CI: 0.01-0.06, p = 0.02) COPD patients and the more comorbidities (B: 0.54, 95% CI: 0.07-1.00, p = 0.02) that they had, the longer the LOS that they experienced. Conclusions: In this study, age and patient comorbidities are independent predictors of LOS in COPD patients in the Anutapura Hospital, Central Sulawesi Province, Indonesia.

Keywords

Length of stay COPD

Article Details

How to Cite
Palipadang, M. N., Manggau, M. A., & Bahar, M. A. (2022). Clinical and Non-Clinical Predictors of Length of Stay in Indonesian hospitalized COPD (Chronic Obstructive Pulmonary Disease) Patients: Prediktor Klinik dan Non-Klinik Lama Rawat Inap Pasien PPOK (Penyakit Paru Obstruktif Kronis) di Rumah Sakit. Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal), 8(2), 132-142. https://doi.org/10.22487/j24428744.2022.v8.i2.16003

References

  1. Agboado, G., Peters, J., & Donkin, L. (2012). Factors influencing the length of hospital stay among patients resident in Blackpool admitted with COPD: A cross-sectional study. BMJ Open, 2(5). https://doi.org/10.1136/bmjopen-2012-000869
  2. Alemu, G. H., Negari, K. G., Rodamo, K. M., & Hirigo, A. T. (2019). Factors associated with the length of stay in emergency departments in Southern-Ethiopia. BMC Research Notes, 12(1). https://doi.org/10.1186/s13104-019-4271-7
  3. Arto Yuwono Soeroto, H. S. (2014). Penyakit Paru Obstruktif Kronik (PPOK). Pedoman Diagnosis & Penatalaksanaan Di Indonesia, 2013, 32. http://www.klikpdpi.com/konsensus/konsensus-ppok/ppok.pdf
  4. Becker, F. G., Cleary, M., Team, R. M., Holtermann, H., The, D., Agenda, N., Science, P., Sk, S. K., Hinnebusch, R., Hinnebusch A, R., Rabinovich, I., Olmert, Y., Uld, D. Q. G. L. Q., Ri, W. K. H. U., Lq, V., Frxqwu, W. K. H., Zklfk, E., Edvhg, L. V, Wkh, R. Q., … فاطمی, ح. (2015). No 主観的健康感を中心とした在宅高齢者における 健康関連指標に関する共分散構造分析Title. Syria Studies, 7(1), 37–72. https://www.researchgate.net/publication/269107473_What_is_governance/link/548173090cf22525dcb61443/download%0Ahttp://www.econ.upf.edu/~reynal/Civil wars_12December2010.pdf%0Ahttps://think-asia.org/handle/11540/8282%0Ahttps://www.jstor.org/stable/41857625
  5. Cavaillès, A., Brinchault-Rabin, G., Dixmier, A., Goupil, F., Gut-Gobert, C., Marchand-Adam, S., Meurice, J. C., Morel, H., Person-Tacnet, C., Leroyer, C., & Diot, P. (2013). Comorbidities of COPD. European Respiratory Review, 22(130), 454–475. https://doi.org/10.1183/09059180.00008612
  6. Díaz-Peromingo, J. A., Grandes-Ibáńez, J., Fandińo-Orgeira, J. M., Barcala-Villamarín, P., & Garrido-Sanjuán, J. A. (2004). Predicting factors contributing to length of stay in hospitalized chronic obstructive pulmonary disease (COPD) patients: the role of the emergency room. Acta Medica (Hradec Králové) / Universitas Carolina, Facultas Medica Hradec Králové, 47(1), 29–32. https://doi.org/10.14712/18059694.2018.62
  7. Harries, T. H., Thornton, H. V., Crichton, S., Schofield, P., Gilkes, A., & White, P. T. (2015). Length of stay of COPD hospital admissions between 2006 and 2010: A retrospective longitudinal study. International Journal of COPD, 10(March), 603–611. https://doi.org/10.2147/COPD.S77092
  8. Huang, J. Q., Hooper, P. M., & Marrie, T. J. (2006). Factors associated with length of stay in hospital for suspected community-acquired pneumonia. Canadian Respiratory Journal, 13(6), 317–324. https://doi.org/10.1155/2006/325087
  9. Inabnit, L. S., Blanchette, C., & Ruban, C. (2018). Comorbidities and length of stay in chronic obstructive pulmonary disease patients. COPD: Journal of Chronic Obstructive Pulmonary Disease, 15(4), 355–360. https://doi.org/10.1080/15412555.2018.1513470
  10. Kemenkes RI. (2019). Hasil Riset Kesehatan Dasar Tahun 2018. Kementrian Kesehatan RI, 53(9), 1689–1699.
  11. Li, M., Cheng, K., Ku, K., Li, J., Hu, H., & Ung, C. O. L. (2021). Factors influencing the length of hospital stay among patients with chronic obstructive pulmonary disease (Copd) in macao population: A retrospective study of inpatient health record. International Journal of COPD, 16(May), 1677–1685. https://doi.org/10.2147/COPD.S307164
  12. Perhimpunan Dokter Paru Indonesia. (2016). P p o k diagnosis dan tatalaksana.
  13. PTM, 2016. (2017). 616.98 Ind p. In Journal of Chemical Information and Modeling (Vol. 53, Issue 9).
  14. Tabachnick, B. G., & Fidell, L. S. (2007). Using multivariate statistics (5th ed.). New York: Harper Collins College Publishers
  15. Tandon, D. S., Budhraja, D. A., Nagdeote, D. S. T., Sharma, D. K., & Shanti Dausage, D. C. (2016). Assessment of length of hospital stays of patients with acute exacerbations of chronic obstructive pulmonary disease. International Journal of Medical Research and Review, 4(1), 97–103. https://doi.org/10.17511/ijmrr.2016.i01.015
  16. University of Nebraska Medical Center. (2016). Antibiotic Guidance for Treatment of Acute Exacerbations of COPD (AECOPD) in Adults. July. https://www.nebraskamed.com/sites/default/files/documents/for-providers/asp/COPD_pathway2016_Final.pdf
  17. Varol, Y., Karakurt, Z., Çırak, A. K., Şahin, H. D., Kıraklı, C., & Kömürcüoğlu, B. (2020). Inappropriate utilization of antibiotics in COPD exacerbations. Turkish Thoracic Journal, 21(6), 397–403. https://doi.org/10.5152/TurkThoracJ.2020.19074
  18. Wang, Y., Stavem, K., Dahl, F. A., Humerfelt, S., & Haugen, T. (2014). Factors associated with a prolonged length of stay after acute exacerbation of chronic obstructive pulmonary disease (AECOPD). International Journal of COPD, 9, 99–105. https://doi.org/10.2147/COPD.S51467
  19. Wong, A. W. M., Gan, W. Q., Burns, J., Sin, D. D., & van Eeden, S. F. (2008). Exacerbation aiguë de la bronchopneumopathie obstructive chronique : Influence des facteurs sociaux sur la durée de l’hospitalisation et les taux de réadmission. Canadian Respiratory Journal, 15(7), 361–364. https://doi.org/10.1155/2008/569496