Article Sidebar

Submitted
Mar 23, 2023
Accepted
Oct 1, 2024
Published
Oct 4, 2024
Download
Statistic
Read Counter : 59

Main Article Content

Abstract

Background: Dengue Fever (DF) is a viral infection disease transmitted by Aedes aegypti. It is one of Indonesian endemic diseases that reported to occur throughout the year. To break the transmission chain of DF, the use of larvicides is preferred, especially using natural ingredients, such as bay leaves (Syzygium polyanthum). Polyethylene glycol (PEG) as a dispersant may prevent the clumping of material test so that it can be distributed evenly in water which is the medium of growth for larvae. Objectives: To determine the effectiveness of ethanolic extract of bay leaves (EEBL) in addition of PEG diluent on the mortality of Aedes aegypti larvae. Material and Method: Bay leaves as the main material were extracted using 95% of ethanol, and were applied in two variation concentration, 0.75% and 1%, while the diluent added was PEG. The samples used in this study were Aedes aegypti larvae at stages III-IV, with a total of 25 individuals for each treatment group. Evaluation was performed every 6 hours, for 24 hours, then the results were recorded and analyzed using the Kruskall Wallis test and the Mann Whitney test. Result: In both of variation concentration used, at 24 hours of observation it was obtained the mortality of Aedes aegypti larvae was 100%. The p-value obtained for the Kruskall Wallis test was <0.05. From Mann Whitney test, when each of treatment group was compared to the positive control, abate®, the p-value obtained is >0.05, while when they were compared to the negative control, PEG, the p-value obtained is <0.05. Conclusion: 95% ethanolic extract of bay leaves in addition of PEG diluent is effective as Aedes aegypti larvicides. It is also known that EEBL at concentration of 0.75% and 1% in addition of PEG are as effective as abate® as Aedes aegypti larvicides.

Keywords

Bay leaves, Larvicide effect, PEG, Aedes aegypti larvae

Article Details

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

How to Cite
Listiana Masyita, D., Tasya Viona, S., Rochmadina Suci, B., & sri, wahyuni. (2024). Larvicidal Activity of Bay Leaf (Syzygium polyanthum) Ethanolic Extract in Addition of PEG Diluent on Aedes aegypti Larvae . Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal), 10(2). https://doi.org/10.22487/j24428744.2024.v10.i2.16335

References

  1. Cahyani, D. N., Asngad, A. (2020). Efektivitas Ekstrak Daun Tembelekan dengan Penambahan Daun Cengkeh Dalam Bentuk Spray Sebagai Insektisida Nabati Terhadap Mortalitas Nyamuk. Seminar Nasional Pendidikan Biologi dan Saintek (SNPBS) ke-V. http://download.garuda.kemdikbud.go.id/article.php?article=2987382&val=26810&title=Efektivitas%20Ekstrak%20Daun%20Tembelekan%20dengan%20Penambahan%20Daun%20Cengkeh%20dalam%20Bentuk%20Spray%20sebagai%20Insektisida%20Nabati%20Terhadap%20Mortalitas%20Nyamuk
  2. Cania, E. B., Setyaningrum, E. (2013). Uji Efektivitas Larvasida Ekstrak Daun
  3. Legundi (Vitex trifolia) Terhadap Larva Aedes aegypti. Medical Journal of Lampung University, 2(4). https://juke.kedokteran.unila.ac.id/index.php/majority/article/viewFile/62/61
  4. de Souza Wuillda, A. C. J., Martins, R. C. C., Costa, F. D. N. (2019).
  5. Larvicidal activity of secondary plant metabolites in aedes aegypti control:
  6. An overview of the previous 6 years. Natural Product
  7. Communications, 14(7), https://journals.sagepub.com/doi/full/10.1177/1934578X19862893
  8. Diah, Y. M., Zulfikar, Z., Ulfa, I., & Hadifah, Z. (2021). Pemetaan Kasus Demam
  9. Berdarah Dengue Dan Kepadatan Nyamuk Berdasarkan Sistem Informasi
  10. Geografis (Sig) Di Wilayah Kerja Puskesmas Lhoknga Kabupaten Aceh
  11. Besar. SEL Jurnal Penelitian Kesehatan, 8(1), 35-46. https://ejournal2.litbang.kemkes.go.id/index.php/sel/article/view/4399
  12. Ervina, N. (2014). Uji Aktivitas Ekstrak Etanol Daun Singkong (Manihot utilissima
  13. Pohl) Sebagai Larvasida Aedes aegypti. Jurnal Mahasiswa PSPD FK
  14. Universitas Tanjungpura, 1(1). https://jurnal.untan.ac.id/index.php/jfk/article/view/8097
  15. Fatimah, H., Isnawati, Zubaidah, T. (2022). Daya Bunuh Larutan Tanaman Daun Salam (Syzygium Polyanthum) Terhadap Kematian Larva Aedes sp. Gema
  16. Lingkungan Kesehatan, 20(1), 71-76. https://gelinkes.poltekkesdepkes-sby.ac.id/index.php/gelinkes/article/view/20
  17. Harismah, K. (2017). Pemanfaatan Daun Salam (Eugenia polyantha) Sebagai Obat
  18. Herbal Dan Rempah Penyedap Makanan. Warta, 19 (2), 110-118. https://journals.ums.ac.id/index.php/warta/article/view/2742/0
  19. Huljani, M., Ahsanunnisa, R. (2019). Pemanfaatan Ekstrak Buah Ketumbar
  20. (Coriandrum sativum L.) sebagai Larvasida Nabati Nyamuk Aedes aegypti.
  21. Prosiding Seminar Nasional Sains dan Teknologi Terapan. Vol. 2, No.
  22. 1. http://semnas.radenfatah.ac.id/index.php/semnasfst/article/view/53
  23. Hutanu, Daniela; Frishberg, Mark, D.; Guo, Ling; Darie, Costel, C. (2014). Recent Applications of Polyethylene Glycols (PEGs) and PEG Derivatives. Mod Chem Appl 2014, 2:2. https://www.researchgate.net/publication/287444069_Recent_Applications_of_Polyethylene_Glycols_PEGs_and_PEG_Derivatives
  24. Kementerian Kesehatan Republik Indonesia. (2022). Profil Kesehatan Indonesia
  25. 2021. https://www.kemkes.go.id/downloads/resources/download/pusdatin/profil-kesehatan-indonesia/Profil-Kesehatan-2021.pdf
  26. Kumara, C. J., Nurhayani, N., Bestari, R. S., Dewi, L. M., (2021). Efektivitas Flavonoid, Tanin, Saponin dan Alkaloid Terhadap Mortalitas Larva Aedes aegypti. Proceeding of The 13th University Research Colloquium 2021: Kesehatan dan MIPA. http://repository.urecol.org/index.php/proceeding/article/view/1311
  27. Riyadi, Z., Julizar, J., Rahmatini, R. (2018). Uji Efektivitas Ekstrak Etanol Biji
  28. Rambutan (Nephelium lappaceum L.) Sebagai Larvasida Alami pada Larva
  29. Nyamuk Aedes aegypti. Jurnal Kesehatan Andalas, 7(2), 233-239. http://jurnal.fk.unand.ac.id/index.php/jka/article/view/807
  30. Setyaningsih, N., Swastika, I. (2016). Efektivitas Ekstrak Ethanol Daun Salam
  31. (Syzygium polyanthum) Sebagai Larvasida Terhadap Larva Nyamuk Aedes
  32. aegypti. E-Jurnal Medika Udayana. 5 (2). https://ojs.unud.ac.id/index.php/eum/article/view/20924
  33. Suparyati, S. (2020). Uji Daya Bunuh Abate Berdasarkan Dosis dan Waktu
  34. Terhadap Kematian Larva Nyamuk Aedes sp dan Culex sp. Pena Jurnal
  35. Ilmu Pengetahuan dan Teknologi, 34(2), 1-9. https://jurnal.unikal.ac.id/index.php/pena/article/view/1193
  36. Susiwati, S., Apriani, K. L., Sahidan. (2017). Efektifitas Ekstrak Infusa Daun Salam
  37. (Syzygium Polyanthum) Sebagai Biolarvasida Nyamuk Aedes sp di Kota
  38. Bengkulu Tahun 2016. Journal of Nursing and Public Health, 5(1), 60-65. https://jurnal.unived.ac.id/index.php/jnph/article/view/599
  39. Syamsir, S. (2018). Analisis Spasial Efektivitas Fogging di Wilayah Kerja
  40. Puskesmas Makroman, Kota Samarinda. Jurnal Nasional Ilmu
  41. Kesehatan, 1(2). https://journal.unhas.ac.id/index.php/jnik/article/view/5996
  42. Lumowa, S. V. T., Nova, T. P. (2015). Larvicidal activity of Syzygium
  43. polyanthum W. Leaf Extract Against Aedes aegypti Larvae. Progress in
  44. Health Sciences, 5(1), 102-106. https://www.umb.edu.pl/photo/pliki/progress-file/phs/phs_2015_1/102-106_lumanowa.pdf
  45. Wang, W. H., Urbina, A. N., Chang, M. R., Assavalapsakul, W., Lu, P. L., Chen,
  46. Y. H., Wang, S. F. (2020). Dengue Hemorrhagic Fever – A Systemic
  47. Literature Review of Current Perspectives on Pathogenesis, Prevention and
  48. Control. Journal of Microbiology, Immunology and Infection, 53(6), 963-
  49. 978. https://pubmed.ncbi.nlm.nih.gov/32265181/
  50. WHO. (2005). Guidelines for Laboratory and Field Testing of Mosquito Larvicides. World Health Organization Communicable Disease Control, Prevention and Eradication - WHO Pesticide Evaluation Scheme. https://www.who.int/publications/i/item/WHO-CDS-WHOPES-GCDPP-2005.13
  51. WHO (2022). Dengue and severe dengue. [online] Who.int.
  52. Available at: https://www.who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue

DB Error: Unknown column 'Array' in 'where clause'