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Submitted
Aug 8, 2024
Accepted
Jan 18, 2025
Published
Mar 3, 2025
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Abstract

The Kedabu fruit, scientifically known as Sonneratia ovata Backer, is a type of mangrove plant commonly found in Indonesia. This fruit is valued for its antioxidant properties and shows potential as a natural sunscreen.. This study is expected to provide an overview and source of information about the potential sunscreen activity of fruit extracts and fractions in vitro by determining the %Te (erythema transmission), %Tp (pigmentation transmission), and FPM (Sun Protection Factor) values. Experiments were conducted on extracts and various fractions, including n-hexane, ethyl acetate, n-butanol, and water. The extracts and fractions of Kedabu fruit were prepared at concentrations of 200, 400, 600, 800, and 1000 μg/mL. Their absorbance was then measured in the UV A (320-375 nm) and UV B (290-320 nm) wavelength ranges. The n-butanol fraction, at a concentration of 1000 μg/mL, appears to be the most effective sunscreen, demonstrating a %Te value of 8.369% and a %Tp of 50.345%. This performance places it in the standard Suntan range for UV B protection. Additionally, it has an FPM value of 10.58, categorizing it within the highest level of sun protection.

Keywords

Kedabu fruit, Suncreen activity, FPM, %Te, %Tp.

Article Details

How to Cite
Lestari, P., Furi, M., Fernando, A., Amin, S., & Irfan, N. (2025). In Vitro Evaluation of Sunscreen Activity of Extract and Fraction of Kedabu Fruit (Sonneratia ovata Backer). Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal), 11(1), 24-33. https://doi.org/10.22487/j24428744.2025.v11.i1.17347

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