KONTROL OPTIMAL PADA PEYEBARAN TUBERKULOSIS DENGAN EXOGENOUS REINFECTION

Abstract

Tuberculosis is a disease caused by Mycobacterium tuberculosis. Tuberculosis can be controlled through treatment, chemoprophylaxis and vaccination. Optimal control of treatment in the exposed compartment can be done in an effort to reduce the number of exposed compartments individual into the active compartment of tuberculosis. Optimal control can be completed by the Pontryagin Maximum Principle Method. Based on numerical simulation results, optimal control of treatment in the exposed compartment can reduce the number of infected compartments individual with active TB.

Keywords : Exogenous Reinfection, Optimal Control, Pontryagin's Maximum Principle, Spread Of Tuberculosis.