Article Sidebar

Submitted
Aug 27, 2020
Accepted
Mar 1, 2021
Published
Mar 3, 2021
Download
PDF
Statistic
Read Counter : 675 Download : 659

Main Article Content

Abstract

Kersen (Muntingia calabura L) fruits have the potential to be used as an active ingredient in sunscreens because of phenolic and flavonoid content that can absorb UV rays. This study aims to determine the percentage of erythema/pigmentation transmission and SPF value as parameters for sunscreen activity.  Kersen fruits were extracted by maceration using 96% ethanol. The ethanol extract of Kersen Fruits was also fractionated to separate the components of the active compounds based on the polarity level using n-hexane, ethyl acetate, and ethanol as solvents. The test was carried out using the in vitro method by measuring the ability of the material to absorb ultraviolet light at a wavelength of 292.5-372.5 nm. This research was conducted at concentrations of 100, 200, 400, 600, and  800 µg/mL for ethanol, lyophilisate, n-hexane, and ethanol fractions, while the ethyl acetate fraction concentrations are 50, 100, 150, 200, 250 µg/mL. The results showed the best value at the ethyl acetate fraction concentration of 250 µg/mL with % Te of 5.28 and % Tp of 28.65 and the SPF value of 16.54. Based on the % Te and Tp, the ethyl acetate fraction exhibited protection against erythema and pigmentation with the category of extra protection and based on the SPF value with the category of ultra protection.

Keywords

Kersen Fruits (Muntingia calabura L) Sunscreen Erhytema Transmission Pigmentation Transmission SPF

Article Details

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

How to Cite
Nur, S., Nursamsiar, N., Aswad, M., Tumigolung, A. E. E., Risfah Yulianti, & Burhan, A. (2021). Screening Bioactivity of Kersen Fruits (Muntingia calabura L.) as a Sunscreens Candidate: Skrining Bioaktivitas dari Buah Kersen (Muntingia calabura L.) sebagai Kandidat Bahan Tabir Surya. Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal), 7(1), 29-38. https://doi.org/10.22487/j24428744.2021.v7.i1.15257

References

  1. Adhi, D., & Aida, S. S. D. (2018). Ilmu Penyakit Kulit Dan Kelamin. In Fkui.
  2. Ahmad Najib. (2018). Ekstraksi Senyawa Bahan Alam. Ekstraksi Senyawa Bahan Alam.
  3. Amiruddin, M. . (2003). Ilmu Penyakit Kulit. Lembaga Penerbitan UNHAS.
  4. Balsam, M. ., & Sagarin, E. (1972). Cosmetics: Science and Technology (Second edi, Vol. 47, Issue 3, p. 285). Wiley-Interscience. https://doi.org/10.1002/jps.3030470334
  5. Cefali, L. C., Ataide, J. A., Moriel, P., Foglio, M. A., & Mazzola, P. G. (2016). Plant-based active photoprotectants for sunscreens. In International Journal of Cosmetic Science. 38(4), 346-353 https://doi.org/10.1111/ics.12316
  6. Cumpelik, B. . (1972). Analitical Procedures and Evaluation of Sunscreens. Journal of the Society of Cosmetics Chemistry, 25(3), 333–345.
  7. Donglikar, M. M., & Deore, S. L. (2016). Sunscreens: A review. Pharmacognosy Journal, 8(3), 171–179. https://doi.org/10.5530/pj.2016.3.1
  8. Dutra, E. A., Da Costa E Oliveira, D. A. G., Kedor-Hackmann, E. R. M., & Miritello Santoro, M. I. R. (2004). Determination of sun protection factor (SPF) of sunscreens by ultraviolet spectrophotometry. Revista Brasileira de Ciencias Farmaceuticas/Brazilian Journal of Pharmaceutical Sciences. M.I, 40(3).https://doi.org/10.1590/S1516-93322004000300014
  9. Fiannisa, R. (2019). Vitamin D sebagai Pencegahan Penyakit Degeneratif hingga Keganasan. Medula. 9(3):385-392.
  10. Halliwell, B., & Gutteridge, J. M. C. (2015). Free Radicals in Biology and Medicine. I New York: Oxford University Press.
  11. Harborne, J. B. (1998). Phytochemical Methods A Guide To Modern Tecniques Of Plant Analysis, Third Edition. Chapman & Hall. https://doi.org/10.1017/CBO9781107415324.004
  12. Hasanah, S., Ahmad, I., & Rijai, L. (2015). Profil Tabir Surya Ekstrak dan Fraksi Daun Pidada Merah (Sonneratia caseolaris L.). Jurnal Sains Dan Kesehatan. 1(4): 175-180. https://doi.org/10.25026/jsk.v1i4.36
  13. Mahmood, N. D., Nasir, N. L. M., Rofiee, M. S., Tohid, S. F. M., Ching, S. M., Teh, L. K., Salleh, M. Z., & Zakaria, Z. A. (2014). Muntingia calabura: A review of its traditional uses, chemical properties, and pharmacological observations. In Pharmaceutical Biology. 52(12): 1598-1623 https://doi.org/10.3109/13880209.2014.908397
  14. Mastuki, S. N., Faudzi, S. M. M., Ismail, N., & Saad, N. (2019). Muntingia calabura: Chemical composition, bioactive component and traditional uses. In Wild Fruits: Composition, Nutritional Value and Products. pp.549-564. https://doi.org/10.1007/978-3-030-31885-7_41
  15. Moore, R. ., & Wilkinson, J. . (1982). Harry’s Cosmeticology 7th Edition (7th Editio). Chemical Publishing Company.
  16. Pakki, E., Murdifin, M., Wijoyo, N., & Sumarheni, S. (2018). Study of sunscreen and antioxidant activity of combination extracts from the red algae Eucheuma cottonii and Eucheuma spinosum. Drug Invention Today. 10(9):1827-1830.
  17. Prasiddha, I. J., Laeliocattleya, R. A., Estiasih, T., & Maligan, J. M. (2016). The Potency of Bioactive Compounds from Corn Silk (Zea mays L.) for the Use as a Natural Sunscreen : A Review. Jurnal Pangan Dan Agroindustri.5(12):175-184.
  18. Pujihastuti, I. (2009). Teknologi Pengawetan Buah Tomat Dengan Metode Freeze Drying. Metana, 6(01), 1–6. https://doi.org/10.14710/metana.v6i01.1948
  19. Saewan, N., & Jimtaisong, A. (2013). Photoprotection of natural flavonoids. Journal of Applied Pharmaceutical Science. 3(09):129-141. https://doi.org/10.7324/JAPS.2013.3923
  20. Sami, F. J., Nur, S., & M, M. M. (2015). Uji Aktivitas Tabir Surya pada Beberapa Spesies dari Family Zingiberaceae dengan Metode Spektrofotometri. As-Syifaa. 7(2):164-173.
  21. Sri Mulyani dan Toga Laksana. (2011). Analisis Flavonoid Dan Tannin Dengan Metoda Mikroskopi- Mikrokimiawi Flavonoid and Tannin Analysis With Microscopy – Microchemical. Majalah Obat Tradisional. 16(3):109 – 114.
  22. Wasitaatmadja, S. M. (1997). Penuntun lmu Kosmetik Medik. In Jakarta: Penerbit Universitas Indonesia.
  23. Wungkana, I., Suryanto, E., & Momuat, L. (2013). Aktivitas Antioksidan Dan Tabir Surya Fraksi Fenolik. Pharmacon Jurnal Ilmiah Farmasi, 2(04), 149–155.

Most read articles by the same author(s)